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Information for Authors
American Journal of Clinical and Experimental Immunology (AJCEI, ISSN: 2164-7712) is an open access
online journal dedicated to rapid publication of research findings in immunology. The scope of AJCEI
encompasses all areas of immunology. AJCEI welcomes original and review articles on both clinical
investigation and basic research. Occasionally, special topic issues, short communications, editorials,
and invited perspectives will also be published. Manuscripts, including figures and tables, must be
original and not under consideration by another journal.
SUBMISSION OF MANUSCRIPT
General Policy
All manuscripts are submitted with the understanding that they have not been published elsewhere
(except in the form of an abstract or as part of a published lecture or thesis) and are not currently under
consideration for publication by another journal. It is the responsibility of the corresponding author to
ensure that all authors have contributed to, read and approved the final manuscript for submission. The
authors should keep a copy of manuscript submitted in case of revision, rejection, loss or damage.
Receipt of manuscript will be acknowledged and a decision regarding acceptance made as soon as
possible. Accepted manuscripts may be subject to editorial revision without notice.
Peer Review Policy
All manuscripts are subject to peer review and are expected to meet the rigorous standards of academic
excellence. Authors should provide 4 potential peer reviewers with detailed contact information including
e-mail address. Authors may also nominate 2 peers that they request are not sent the article for peer
review for conflicts of interest or other appropriate reasons – in such instances some reasonable
justification must be given. These should be experts in their field of study, who will be able to provide an
objective assessment of the manuscript. If not provided, potential reviewers will be identified by their
publication record or recommended by the Editorial Board members.
Copyright Policy
By submitting a manuscript to AJCEI, all authors agree that all copyrights of all materials included in the
submitted manuscript will be exclusively transferred to the publisher - e-Century Publishing Corporation
once the manuscript is accepted.
Once the paper is published, the copyright will be released by the publisher under the “Creative
Commons Attribution Noncommercial License”, enabling the unrestricted non-commercial use,
distribution, and reproduction of the published article in any medium, provided that the original work is
properly cited. If the manuscript contains a figure or table reproduced from a book or another journal
article, the authors should obtain permission from the copyright holder before submitting the manuscript,
and be fully responsible for any legal and/or financial consequences if such permissions are not
obtained.
All PDF, XML and html files for all articles published in this journal are the property of the publisher, e-
Century Publishing Corporation (www.e-Century.org). Authors and readers are granted the right to
freely use these files for all academic purposes. By publishing paper in this journal, the authors grant
the permanent right to the publisher to use any articles published in this journal without any restriction
including, but not limited to academic and/or commercial purposes. If you are interested in using PDF,
html, XML files or any art works published in this journal for any commercial purposes, please contact
the publisher at business@e-century.org.
Use of Human Subjects/Human Tissue and/or Animal Policy
Experiments involving human subjects should be done in accordance with the relevant ethical and legal
standards established and accepted by their host institution or in accordance with the Helsinki
Declaration of 1975, or the Guidelines of Office for Human Research Protections (OHRP) Human
Subject Protections or equivalent. For studies that involved human subjects, when informed consent has
been obtained it should be indicated in the manuscript.
Experiments involving animals should follow the appropriate institution or the National Research Council
Guide for the care and use of laboratory animals.
Units and Abbreviations
System International (SI) units should be used for all measurements. All abbreviations should be
explicitly defined at their first occurrence except for those internationally acceptable. Abbreviations used
in the genetic association reports will need to follow the conventions detailed in the specific information
requirements for genetic association reports. Any articles that involve the description of enzymes will
require the inclusion of the appropriate EC (Enzyme Commission) number as recommended by the
Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (IUBMB).
Disclaimer
While the advice and information in the article are believed to be true and accurate on the date of its
going to press, neither the authors nor the editors can accept any legal responsibilities for any errors or
omissions that may be made. The publication makes no warranty, expressed or implied, with respect to
the materials contained within.
PREPARATION OF MANUSCRIPT
All manuscripts should be written in standard grammatical English using computer software (Franklin
Gothic Book normal font, size 12, with single spacing between lines) and should be saved as single DOC
(Word) file. Main Research Articles and Brief Communications will follow a similar format as outlined
below while Review Articles will follow a variation on this (see below).
Main Research Articles are defined as being a substantial novel research study discussing the
investigation of a clear hypothesis or research question with appropriate methodologies (the use of
more than one approach is encouraged) and adequately powered studies and sample sizes. Noting the
relevant sections (see below) there is no word limit on manuscripts of this type except for the Abstract
which should be a single unreferenced paragraph and no more than 350 words. There are no limits on
the number of display items (tables and/or figures) although authors should try to be concise and only
include the most pertinent information. There are no supplementary tables or figures and every effort
should be made to include these in the main manuscript or alternatively reference should be made in
the appropriate locations of the manuscripts that such information will be available on request from the
corresponding authors. There is no limit on the number of references.
Brief Communications are a format that accommodates the reporting of high quality completed smaller
scale studies. This format is not for the reporting of preliminary or incomplete findings and the review
process is equally rigorous as that for Main Articles. The sections of a Brief Communication follow those
of Main Articles (see below) and there should not be additional sub-headings within these sections.
Review articles have a flexible format, are not of restricted length or reference number. Submissions of
reviews must follow that of Main Research Articles (see below) with the exception that appropriate
headings be included for the main text of the manuscript.
Layout requirements for submissions of Main Research Articles or Brief Communications:
1. cover letter
2. title page
3. abstract and keywords
4. main text
5. acknowledgements, if any
6 Declaration of conflicts of interest, if any
7. References
8. tables, if any
9. figure legends, if any
10. figures, if any
Cover Letter
The cover letter should include name, degree, address, telephone, fax and email of the corresponding
author. A statement that all authors have contributed to, read and approved the final manuscript for
submission should be included if there are multiple authors. Any editorial or financial conflict of interest
(e.g., consultancy, stock ownership, equity interests, patent or licensing agreements) should be clearly
disclosed in the cover letter. The disclosure statement must be submitted upon the acceptance. The
cover letter should also be used to provide up the relevant details of 4 potential reviewers and 2 non-
reviewers for your manuscript giving appropriate explanations for the latter. Finally, if this submission is
following the solicitation or invitation of an Editorial Board member please state by whom.
Title Page
1. a concise title;
2. first name, middle initial, and last name of each author;
3. name of the department and institutional affiliation of each author.
4. the email address of each author.(*)
5. a running title.
(*) AJCEI will only use the email address of the designated corresponding author in the final published
manuscript but will use all email addresses supplied to copy in all authors as additional email
respondents to the correspondences we routinely send to acknowledge receipt of manuscripts, and final
decisions made on submitted manuscripts. AJCEI would also like, unless otherwise directed in the
manuscript covering letter, to use these contact details to announce the contents lists of future issues of
AJCEI and its sister journals! At no stage will AJCEI sell such email lists to parties external to the e-
Century Publishing Corporation.
Abstract and Key Words
Abstract should not exceed 350 words that concisely summarize the study’s purpose, significant findings
and conclusions. Include up to 10 key words or phrases at the end of the abstract.
Main Text
The main text should include Introduction, Materials and Methods, Results and Discussion. The
Introduction should be succinct, clearly stating the purpose and rationale of the study. In Materials and
Methods, the procedures should be described in sufficient detail to allow duplication by an independent
observer. Results and Discussion should be divided. They should be written concisely and logically with
emphasis on novel findings and minimal repetition of text. For genetic association reports refer to
specific information requirements.
Acknowledgements
All acknowledgements (if any) should be included at the end of the main text before references and may
include grant and administrative support.
References (Please download EndNote X Style or Reference Manager Output Style for AJCEI)
Reference published in AJCEI should begin on a new page, be single-spaced and numbered in order of
citation in the text, including citations in tables and figure legends. Complete author citation is required
(use of "et al" is not acceptable). References should conform to the style of the Journal. Examples follow:
Journals: [1] Yin M, Hu Z, Tan D, Ajani JA, Wei Q. Molecular epidemiology of genetic susceptibility to
gastric cancer: focus on single nucleotide polymorphisms in gastric carcinogenesis. Am J Transl Res
2009;1:44-54.
Books: Fishman AP: Pulmonary Hypertension and Cor Pulmonale. Pulmonary Diseases and Disorders.
Edited by Fishman AP. New York, McGraw-Hill, 1988, pp. 999-1048
Web sites: Cite in text only using the appropriate URL. It is the author’s responsibility at the time of
submission and subsequent publication that the website address is relevant and functional.
In press: To be used only for papers accepted for publication. Cite as for journal with (in press) in place
of volume and page numbers.
Personal Communications: to be used very sparingly and in the context of no more than one sentence
of associated text.
Submitted papers/unpublished data: Cite in text only.
Tables
All tables should be created with Microsoft Word Table Tool, single spacing between rows and cited
consecutively in the main text by Arabic numbers (Table 1, Table 2, etc). Include each table with a
descriptive title on a separate page after the references. Provide explanations for any nonstandard
abbreviations in footnotes to the table.
All tables should be included in the Word File as the part of the complete manuscript after bibliography.
Tables in image or other formats are not acceptable. Authors are encouraged to split extremely large
tables into multiple smaller ones to facilitate publication and easiness to readers.
Figure Legends
Figure legends including figure number, a short title and detailed description should be embedded at
the end of text file.
Figures
All figures should be cited consecutively in the main text by Arabic numbers (Figure 1, Figure 2, etc). All
figures must be submitted in TIFF or JPEG format as separate files labeled with the corresponding
numbers. Photographs of a person should render them unidentifiable or include their written permission.
Any figures involving Copyright issues should conform to the Copyright policy.
Publication Fees
American Journal of Clinical and Experimental Immunology is an open access journal which provides
instant, worldwide and barrier-free access to the full-text of all published articles. Publication charges
allow the publisher to make the published material available for free to all interested online readers.
The Publishing fee is $980 per article. Editorial board members are entitled to a 30% discount. This will
be billed to the corresponding author. There is no extra charge for color figures. Authors who do not
have appropriate funds from developing countries can apply to have the reduced fee by submitting a
letter signed by the departmental chair to state such a fact. Editorial decisions are not contingent upon
the ability to pay publication charges.
Manuscript Submission
The journal invites submission of all original research and review articles, editorials, and letters to the
editor. All manuscripts should be submitted via email to: editorial@AJCEI.us and should be in
compliance with the author’s guidelines described above. Please visit submission for further information.
American Journal of Clinical and Experimental Immunology (AJCEI, ISSN: 2164-7712) is an open access
online journal dedicated to rapid publication of research findings in immunology. The scope of AJCEI
encompasses all areas of immunology. AJCEI welcomes original and review articles on both clinical
investigation and basic research. Occasionally, special topic issues, short communications, editorials,
and invited perspectives will also be published. Manuscripts, including figures and tables, must be
original and not under consideration by another journal.
SUBMISSION OF MANUSCRIPT
General Policy
All manuscripts are submitted with the understanding that they have not been published elsewhere
(except in the form of an abstract or as part of a published lecture or thesis) and are not currently under
consideration for publication by another journal. It is the responsibility of the corresponding author to
ensure that all authors have contributed to, read and approved the final manuscript for submission. The
authors should keep a copy of manuscript submitted in case of revision, rejection, loss or damage.
Receipt of manuscript will be acknowledged and a decision regarding acceptance made as soon as
possible. Accepted manuscripts may be subject to editorial revision without notice.
Peer Review Policy
All manuscripts are subject to peer review and are expected to meet the rigorous standards of academic
excellence. Authors should provide 4 potential peer reviewers with detailed contact information including
e-mail address. Authors may also nominate 2 peers that they request are not sent the article for peer
review for conflicts of interest or other appropriate reasons – in such instances some reasonable
justification must be given. These should be experts in their field of study, who will be able to provide an
objective assessment of the manuscript. If not provided, potential reviewers will be identified by their
publication record or recommended by the Editorial Board members.
Copyright Policy
By submitting a manuscript to AJCEI, all authors agree that all copyrights of all materials included in the
submitted manuscript will be exclusively transferred to the publisher - e-Century Publishing Corporation
once the manuscript is accepted.
Once the paper is published, the copyright will be released by the publisher under the “Creative
Commons Attribution Noncommercial License”, enabling the unrestricted non-commercial use,
distribution, and reproduction of the published article in any medium, provided that the original work is
properly cited. If the manuscript contains a figure or table reproduced from a book or another journal
article, the authors should obtain permission from the copyright holder before submitting the manuscript,
and be fully responsible for any legal and/or financial consequences if such permissions are not
obtained.
All PDF, XML and html files for all articles published in this journal are the property of the publisher, e-
Century Publishing Corporation (www.e-Century.org). Authors and readers are granted the right to
freely use these files for all academic purposes. By publishing paper in this journal, the authors grant
the permanent right to the publisher to use any articles published in this journal without any restriction
including, but not limited to academic and/or commercial purposes. If you are interested in using PDF,
html, XML files or any art works published in this journal for any commercial purposes, please contact
the publisher at business@e-century.org.
Use of Human Subjects/Human Tissue and/or Animal Policy
Experiments involving human subjects should be done in accordance with the relevant ethical and legal
standards established and accepted by their host institution or in accordance with the Helsinki
Declaration of 1975, or the Guidelines of Office for Human Research Protections (OHRP) Human
Subject Protections or equivalent. For studies that involved human subjects, when informed consent has
been obtained it should be indicated in the manuscript.
Experiments involving animals should follow the appropriate institution or the National Research Council
Guide for the care and use of laboratory animals.
Units and Abbreviations
System International (SI) units should be used for all measurements. All abbreviations should be
explicitly defined at their first occurrence except for those internationally acceptable. Abbreviations used
in the genetic association reports will need to follow the conventions detailed in the specific information
requirements for genetic association reports. Any articles that involve the description of enzymes will
require the inclusion of the appropriate EC (Enzyme Commission) number as recommended by the
Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (IUBMB).
Disclaimer
While the advice and information in the article are believed to be true and accurate on the date of its
going to press, neither the authors nor the editors can accept any legal responsibilities for any errors or
omissions that may be made. The publication makes no warranty, expressed or implied, with respect to
the materials contained within.
PREPARATION OF MANUSCRIPT
All manuscripts should be written in standard grammatical English using computer software (Franklin
Gothic Book normal font, size 12, with single spacing between lines) and should be saved as single DOC
(Word) file. Main Research Articles and Brief Communications will follow a similar format as outlined
below while Review Articles will follow a variation on this (see below).
Main Research Articles are defined as being a substantial novel research study discussing the
investigation of a clear hypothesis or research question with appropriate methodologies (the use of
more than one approach is encouraged) and adequately powered studies and sample sizes. Noting the
relevant sections (see below) there is no word limit on manuscripts of this type except for the Abstract
which should be a single unreferenced paragraph and no more than 350 words. There are no limits on
the number of display items (tables and/or figures) although authors should try to be concise and only
include the most pertinent information. There are no supplementary tables or figures and every effort
should be made to include these in the main manuscript or alternatively reference should be made in
the appropriate locations of the manuscripts that such information will be available on request from the
corresponding authors. There is no limit on the number of references.
Brief Communications are a format that accommodates the reporting of high quality completed smaller
scale studies. This format is not for the reporting of preliminary or incomplete findings and the review
process is equally rigorous as that for Main Articles. The sections of a Brief Communication follow those
of Main Articles (see below) and there should not be additional sub-headings within these sections.
Review articles have a flexible format, are not of restricted length or reference number. Submissions of
reviews must follow that of Main Research Articles (see below) with the exception that appropriate
headings be included for the main text of the manuscript.
Layout requirements for submissions of Main Research Articles or Brief Communications:
1. cover letter
2. title page
3. abstract and keywords
4. main text
5. acknowledgements, if any
6 Declaration of conflicts of interest, if any
7. References
8. tables, if any
9. figure legends, if any
10. figures, if any
Cover Letter
The cover letter should include name, degree, address, telephone, fax and email of the corresponding
author. A statement that all authors have contributed to, read and approved the final manuscript for
submission should be included if there are multiple authors. Any editorial or financial conflict of interest
(e.g., consultancy, stock ownership, equity interests, patent or licensing agreements) should be clearly
disclosed in the cover letter. The disclosure statement must be submitted upon the acceptance. The
cover letter should also be used to provide up the relevant details of 4 potential reviewers and 2 non-
reviewers for your manuscript giving appropriate explanations for the latter. Finally, if this submission is
following the solicitation or invitation of an Editorial Board member please state by whom.
Title Page
1. a concise title;
2. first name, middle initial, and last name of each author;
3. name of the department and institutional affiliation of each author.
4. the email address of each author.(*)
5. a running title.
(*) AJCEI will only use the email address of the designated corresponding author in the final published
manuscript but will use all email addresses supplied to copy in all authors as additional email
respondents to the correspondences we routinely send to acknowledge receipt of manuscripts, and final
decisions made on submitted manuscripts. AJCEI would also like, unless otherwise directed in the
manuscript covering letter, to use these contact details to announce the contents lists of future issues of
AJCEI and its sister journals! At no stage will AJCEI sell such email lists to parties external to the e-
Century Publishing Corporation.
Abstract and Key Words
Abstract should not exceed 350 words that concisely summarize the study’s purpose, significant findings
and conclusions. Include up to 10 key words or phrases at the end of the abstract.
Main Text
The main text should include Introduction, Materials and Methods, Results and Discussion. The
Introduction should be succinct, clearly stating the purpose and rationale of the study. In Materials and
Methods, the procedures should be described in sufficient detail to allow duplication by an independent
observer. Results and Discussion should be divided. They should be written concisely and logically with
emphasis on novel findings and minimal repetition of text. For genetic association reports refer to
specific information requirements.
Acknowledgements
All acknowledgements (if any) should be included at the end of the main text before references and may
include grant and administrative support.
References (Please download EndNote X Style or Reference Manager Output Style for AJCEI)
Reference published in AJCEI should begin on a new page, be single-spaced and numbered in order of
citation in the text, including citations in tables and figure legends. Complete author citation is required
(use of "et al" is not acceptable). References should conform to the style of the Journal. Examples follow:
Journals: [1] Yin M, Hu Z, Tan D, Ajani JA, Wei Q. Molecular epidemiology of genetic susceptibility to
gastric cancer: focus on single nucleotide polymorphisms in gastric carcinogenesis. Am J Transl Res
2009;1:44-54.
Books: Fishman AP: Pulmonary Hypertension and Cor Pulmonale. Pulmonary Diseases and Disorders.
Edited by Fishman AP. New York, McGraw-Hill, 1988, pp. 999-1048
Web sites: Cite in text only using the appropriate URL. It is the author’s responsibility at the time of
submission and subsequent publication that the website address is relevant and functional.
In press: To be used only for papers accepted for publication. Cite as for journal with (in press) in place
of volume and page numbers.
Personal Communications: to be used very sparingly and in the context of no more than one sentence
of associated text.
Submitted papers/unpublished data: Cite in text only.
Tables
All tables should be created with Microsoft Word Table Tool, single spacing between rows and cited
consecutively in the main text by Arabic numbers (Table 1, Table 2, etc). Include each table with a
descriptive title on a separate page after the references. Provide explanations for any nonstandard
abbreviations in footnotes to the table.
All tables should be included in the Word File as the part of the complete manuscript after bibliography.
Tables in image or other formats are not acceptable. Authors are encouraged to split extremely large
tables into multiple smaller ones to facilitate publication and easiness to readers.
Figure Legends
Figure legends including figure number, a short title and detailed description should be embedded at
the end of text file.
Figures
All figures should be cited consecutively in the main text by Arabic numbers (Figure 1, Figure 2, etc). All
figures must be submitted in TIFF or JPEG format as separate files labeled with the corresponding
numbers. Photographs of a person should render them unidentifiable or include their written permission.
Any figures involving Copyright issues should conform to the Copyright policy.
Publication Fees
American Journal of Clinical and Experimental Immunology is an open access journal which provides
instant, worldwide and barrier-free access to the full-text of all published articles. Publication charges
allow the publisher to make the published material available for free to all interested online readers.
The Publishing fee is $980 per article. Editorial board members are entitled to a 30% discount. This will
be billed to the corresponding author. There is no extra charge for color figures. Authors who do not
have appropriate funds from developing countries can apply to have the reduced fee by submitting a
letter signed by the departmental chair to state such a fact. Editorial decisions are not contingent upon
the ability to pay publication charges.
Manuscript Submission
The journal invites submission of all original research and review articles, editorials, and letters to the
editor. All manuscripts should be submitted via email to: editorial@AJCEI.us and should be in
compliance with the author’s guidelines described above. Please visit submission for further information.
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